In an effort to bring novel diagnostic and prognostic biomarkers or even potential targets for
vaccine design for systemic candidiasis (SC) into the open, a systematic proteomic
approach coupled with bioinformatic analysis was used to decode the serological response
to Candida wall immunome in SC patients. Serum levels of IgG antibodies against Candida
wall-associated proteins (proteins secreted from protoplasts in active wall regeneration,
separated by two-dimensional gel electrophoresis, and identified by mass spectrometry) …