[PDF][PDF] Cytokines: shared receptors, distinct functions
JP DiSanto - Current biology, 1997 - cell.com
JP DiSanto
Current biology, 1997•cell.comThat the signal transduction pathways used by the cytokines IL-2 and IL-15 are identical
would suggest that these cytokines have redundant roles in lymphoid development; instead,
IL-2 is the guardian of thymus-derived T-cell homeostasis, while interleukin-15 promotes
extrathymic development of T and NK cells.
would suggest that these cytokines have redundant roles in lymphoid development; instead,
IL-2 is the guardian of thymus-derived T-cell homeostasis, while interleukin-15 promotes
extrathymic development of T and NK cells.
Abstract
That the signal transduction pathways used by the cytokines IL-2 and IL-15 are identical would suggest that these cytokines have redundant roles in lymphoid development; instead, IL-2 is the guardian of thymus-derived T-cell homeostasis, while interleukin-15 promotes extrathymic development of T and NK cells.
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