[HTML][HTML] Prolonged leucine supplementation does not augment muscle mass or affect glycemic control in elderly type 2 diabetic men
M Leenders, LB Verdijk, L van der Hoeven… - The Journal of …, 2011 - Elsevier
The loss of muscle mass with aging has been, at least partly, attributed to a blunted muscle
protein synthetic response to food intake. Leucine coingestion has been reported to
stimulate postprandial insulin release and augment postprandial muscle protein accretion.
We assessed the clinical benefits of 6 mo of leucine supplementation in elderly, type 2
diabetes patients. Sixty elderly males with type 2 diabetes (age, 71±1 y; BMI, 27.3±0.4 kg/m
2) were administered 2.5 g ʟ-leucine (n= 30) or a placebo (n= 30) with each main meal …
protein synthetic response to food intake. Leucine coingestion has been reported to
stimulate postprandial insulin release and augment postprandial muscle protein accretion.
We assessed the clinical benefits of 6 mo of leucine supplementation in elderly, type 2
diabetes patients. Sixty elderly males with type 2 diabetes (age, 71±1 y; BMI, 27.3±0.4 kg/m
2) were administered 2.5 g ʟ-leucine (n= 30) or a placebo (n= 30) with each main meal …