Total knee replacement (TKR) is considered an effective intervention for the treatment of
chronic knee pain and disability. Yet there is increasing evidence, based on research using
patient-based outcome measures, that a significant proportion of patients experience
chronic knee pain, functional disability, a poor quality of life and dissatisfaction after TKR.
Although some poor outcomes after TKR are due to surgical technique and implant factors,
much of the pain and disability after surgery is medically unexplained. A range of possible …