BACKGROUND: Cutaneous burn distant from skeletal muscles induces atrophy; however,
its effect on muscle stem cells resident in skeletal muscle (satellite cells) distal to burn is not
known. METHODS: Satellite cell activation was measured in predominantly fast-twitch
[tibialis anterior, extensor digitorum longus (EDL), plantaris, and gastrocnemius] and slow-
twitch (soleus) muscles of rats that received either 40% total body surface area full-thickness
scald burn or sham burn to the trunk area by determining bromodeoxyuridine incorporation …