[HTML][HTML] Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein
Eukaryotic GCN5 acetyltransferases influence diverse biological processes by acetylating
histones and non-histone proteins and regulating chromatin and gene-specific transcription
as part of multiprotein complexes. In lower eukaryotes and invertebrates, these complexes
include the yeast ADA complex that is still incompletely understood; the SAGA (Spt-Ada-
Gcn5 acetylase) complexes from yeast to Drosophila that are mostly coactivators; and the
ATAC (Ada Two-A containing) complex, only known in Drosophila and still poorly …
histones and non-histone proteins and regulating chromatin and gene-specific transcription
as part of multiprotein complexes. In lower eukaryotes and invertebrates, these complexes
include the yeast ADA complex that is still incompletely understood; the SAGA (Spt-Ada-
Gcn5 acetylase) complexes from yeast to Drosophila that are mostly coactivators; and the
ATAC (Ada Two-A containing) complex, only known in Drosophila and still poorly …