P311 is a mouse cDNA originally identified for its high expression in late-stage embryonic
brain and adult cerebellum, hippocampus, and olfactory bulb. The protein product of P311,
however, had not been identified previously, and its function remains unknown. We report
here that P311 expression is regulated at multiple levels by pathways that control cellular
transformation. P311 mRNA expression was decreased sharply in both neural and smooth
muscle cells when the cells were transformed by coexpression of the oncogenic tyrosine …