Direct enumeration and functional assessment of circulating dendritic cells in patients with liver disease
AM Wertheimer, A Bakke, HR Rosen - Hepatology, 2004 - journals.lww.com
Chronic liver disease has been shown to be associated with diminished humoral and
cellular immune function. Although antigen-presenting cells (APC) that initiate immune
responses include various cells (B cells, endothelial cells, macrophages, etc.), the dendritic
cell (DC) is a professional APC that activates naive T cells most efficiently. To examine the
frequency and function of DCs in chronic liver disease, we studied circulating DCs from a
cohort of 112 subjects (23 normal subjects, 29 subjects who had spontaneously recovered …
cellular immune function. Although antigen-presenting cells (APC) that initiate immune
responses include various cells (B cells, endothelial cells, macrophages, etc.), the dendritic
cell (DC) is a professional APC that activates naive T cells most efficiently. To examine the
frequency and function of DCs in chronic liver disease, we studied circulating DCs from a
cohort of 112 subjects (23 normal subjects, 29 subjects who had spontaneously recovered …