A new take on tau

J Marx - Science, 2007 - science.org
J Marx
Science, 2007science.org
When tau goes bad. In a normal neuron (top), tau stabilizes the microtubules (blue lines) that
transport materials to the nerve terminals. But in Alzheimer's disease, tau loses its ability to
bind to the microtubules and forms abnormal aggregates. The microtubules degenerate,
impairing neuronal function.
When tau goes bad. In a normal neuron (top), tau stabilizes the microtubules (blue lines) that transport materials to the nerve terminals. But in Alzheimer’s disease, tau loses its ability to bind to the microtubules and forms abnormal aggregates. The microtubules degenerate, impairing neuronal function.
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