The acute blockade of spinal glycinergic inhibition with intrathecal strychnine (it STR; a
glycine antagonist) in rats induces a change in somatosensory processing which is very
similar to the sensory dysesthesia of clinical neural injury pain. In the present study, the
effects of it STR were examined in urethane-anesthetized rats. Noxious paw pinch (PP) or
tail immersion (TI) in 55° C water evoked a pronounced pressor response, increased heart
rate (HR) and desynchronized the electroencephalogram; a non-noxious, hair deflection …