Functions of claudin tight junction proteins and their complex interactions in various physiological systems
L Elkouby-Naor, T Ben-Yosef - International review of cell and molecular …, 2010 - Elsevier
Members of the claudin family of proteins are the main components of tight junctions (TJs),
the major selective barrier of the paracellular pathway between epithelial cells. As such, the
claudins have the ability to generate the TJ physiological barrier and to control various
physiological processes. Therefore, the importance of this family of proteins is obvious and
many efforts were made to reveal different aspects of claudin TJ protein biology. In this
review, we discuss recent advances in our understanding of claudin structure and function …
the major selective barrier of the paracellular pathway between epithelial cells. As such, the
claudins have the ability to generate the TJ physiological barrier and to control various
physiological processes. Therefore, the importance of this family of proteins is obvious and
many efforts were made to reveal different aspects of claudin TJ protein biology. In this
review, we discuss recent advances in our understanding of claudin structure and function …