Global initiative for chronic obstructive lung disease stage 0 is associated with excess FEV1 decline in a representative population sample
R Brito-Mutunayagam, SL Appleton, DH Wilson… - Chest, 2010 - Elsevier
Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline
removed stage 0 (chronic cough and sputum without airflow obstruction, GOLD-0) because
of poor prognostic value. Preventative intervention may be relevant for those with chronic
symptoms; therefore, we assessed the stability, morbidity, and FEV 1 decline associated with
GOLD stage 0 in a representative adult population cohort. Methods Baseline (n= 4,060) and
follow-up (n= 3,206, mean 3.5 years) clinic assessment of the North West Adelaide Health …
removed stage 0 (chronic cough and sputum without airflow obstruction, GOLD-0) because
of poor prognostic value. Preventative intervention may be relevant for those with chronic
symptoms; therefore, we assessed the stability, morbidity, and FEV 1 decline associated with
GOLD stage 0 in a representative adult population cohort. Methods Baseline (n= 4,060) and
follow-up (n= 3,206, mean 3.5 years) clinic assessment of the North West Adelaide Health …