[HTML][HTML] Single vs. swarm detection of microparticles and exosomes by flow cytometry

E Van Der Pol, MJC Van Gemert, A Sturk… - Journal of Thrombosis …, 2012 - Elsevier
See also Harrison P, Gardiner C. Invisible vesicles swarm within the iceberg. This issue, pp
916‐8. Summary. Background: Microparticles and exosomes are cell‐derived vesicles and
potential biomarkers for disease. Recently, the Scientific Standardization Committee
collaborative workshop of the ISTH initiated standardization of vesicle detection by flow
cytometry with polystyrene beads. Because polystyrene beads have different optical
properties from biological vesicles, and because the mechanisms causing the detection …