[HTML][HTML] Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA …
W Annema, N Nijstad, M Tölle, JF de Boer… - Journal of lipid …, 2010 - ASBMB
Atherosclerosis is linked to inflammation. HDL protects against atherosclerotic
cardiovascular disease, mainly by mediating cholesterol efflux and reverse cholesterol
transport (RCT). The present study aimed to test the impact of acute inflammation as well as
selected acute phase proteins on RCT with a macrophage-to-feces in vivo RCT assay using
intraperitoneal administration of [3 H] cholesterol-labeled macrophage foam cells. In patients
with acute sepsis, cholesterol efflux toward plasma and HDL were significantly decreased …
cardiovascular disease, mainly by mediating cholesterol efflux and reverse cholesterol
transport (RCT). The present study aimed to test the impact of acute inflammation as well as
selected acute phase proteins on RCT with a macrophage-to-feces in vivo RCT assay using
intraperitoneal administration of [3 H] cholesterol-labeled macrophage foam cells. In patients
with acute sepsis, cholesterol efflux toward plasma and HDL were significantly decreased …