[HTML][HTML] Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after …

T Ichimura, JV Bonventre, V Bailly, H Wei… - Journal of Biological …, 1998 - ASBMB
We report the identification of rat and human cDNAs for a type 1 membrane protein that
contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is named
kidney injury molecule-1 (KIM-1). Structurally, KIM-1 is a member of the immunoglobulin
gene superfamily most reminiscent of mucosal addressin cell adhesion molecule 1
(MAdCAM-1). Human KIM-1 exhibits homology to a monkey gene, hepatitis A virus cell
receptor 1 (HAVcr-1), which was identified recently as a receptor for the hepatitis A virus …