Prognostic factors in ovarian cancer: how close are we to a complete picture?
R Agarwal, SB Kaye - Annals of Oncology, 2005 - annalsofoncology.org
Ovarian cancer is the fourth most common cause of cancerrelated death in women, but is the
most lethal of the gynaecological malignancies with 30–40% overall survival at 5 years [1].
This is in part because the majority of patients with ovarian cancer present with advanced
disease, and treatment options at presentation are confined to a combination of debulking
surgery and platinum based chemotherapy, which are only partially effective [2].
Consequently, almost all patients with advanced disease ultimately relapse and die of their …
most lethal of the gynaecological malignancies with 30–40% overall survival at 5 years [1].
This is in part because the majority of patients with ovarian cancer present with advanced
disease, and treatment options at presentation are confined to a combination of debulking
surgery and platinum based chemotherapy, which are only partially effective [2].
Consequently, almost all patients with advanced disease ultimately relapse and die of their …