Critical appraisal of the current practice in murine TNBS-induced colitis

AA te Velde, MI Verstege… - Inflammatory bowel …, 2006 - academic.oup.com
AA te Velde, MI Verstege, DW Hommes
Inflammatory bowel diseases, 2006academic.oup.com
There is no standard practice in the induction of colitis by 2, 4, 6-trinitrobenzene sulfonic
acid. In this review the current practice in 2, 4, 6-trinitrobenzene sulfonic acid colitis is
studied using 20 recently published articles. We compare the different protocols, discuss the
mechanism of disease and give recommendations for the future use of the model.
Abstract
There is no standard practice in the induction of colitis by 2,4,6-trinitrobenzene sulfonic acid. In this review the current practice in 2,4,6-trinitrobenzene sulfonic acid colitis is studied using 20 recently published articles. We compare the different protocols, discuss the mechanism of disease and give recommendations for the future use of the model.
Oxford University Press