[HTML][HTML] 1, 25-Dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease
MT Cantorna, C Munsick, C Bemiss, BD Mahon - The Journal of nutrition, 2000 - Elsevier
Anecdotal data suggest that the amount of vitamin D available in the environment either from
sunshine exposure or diet may be an important factor affecting the development of
inflammatory bowel disease (IBD) in humans. We tested the vitamin D hypothesis in an
experimental animal model of IBD. Interleukin (IL)-10 knockout (KO) mice, which
spontaneously develop symptoms resembling human IBD, were made vitamin D deficient,
vitamin D sufficient or supplemented with active vitamin D (1, 25-dihydroxycholecalciferol) …
sunshine exposure or diet may be an important factor affecting the development of
inflammatory bowel disease (IBD) in humans. We tested the vitamin D hypothesis in an
experimental animal model of IBD. Interleukin (IL)-10 knockout (KO) mice, which
spontaneously develop symptoms resembling human IBD, were made vitamin D deficient,
vitamin D sufficient or supplemented with active vitamin D (1, 25-dihydroxycholecalciferol) …