A new human cell line (FaDu) from a hypopharyngeal carcinoma

SRS Rangan - Cancer, 1972 - Wiley Online Library
SRS Rangan
Cancer, 1972Wiley Online Library
A human epithelial cell line, FaDu, from a squamous cell carcinoma of the hypopharynx has
been isolated and established from a patient from Calcutta, India. The cell line has a
population doubling time of approximately 50 hours. Ultrastructural observation reveals the
presence of bundles of tonofilaments in the cells and desmosomal regions distributed at the
boundaries of adjacent cells. The cell line is susceptible to infection by some RNA‐and DNA‐
containing viruses.
Abstract
A human epithelial cell line, FaDu, from a squamous cell carcinoma of the hypopharynx has been isolated and established from a patient from Calcutta, India. The cell line has a population doubling time of approximately 50 hours. Ultrastructural observation reveals the presence of bundles of tonofilaments in the cells and desmosomal regions distributed at the boundaries of adjacent cells. The cell line is susceptible to infection by some RNA‐ and DNA‐containing viruses.
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