Physiological roles revealed by ghrelin and ghrelin receptor deficient mice
RG Albarran-Zeckler, Y Sun, RG Smith - Peptides, 2011 - Elsevier
Ghrelin is a hormone made in the stomach and known primarily for its growth hormone
releasing and orexigenic properties. Nevertheless, ghrelin through its receptor, the GHS-
R1a, has been shown to exert many roles including regulation of glucose homeostasis,
memory & learning, food addiction and neuroprotection. Furthermore, ghrelin could promote
overall health and longevity by acting directly in the immune system and promoting an
extended antigen repertoire. The development of mice lacking either ghrelin (ghrelin−/−) or …
releasing and orexigenic properties. Nevertheless, ghrelin through its receptor, the GHS-
R1a, has been shown to exert many roles including regulation of glucose homeostasis,
memory & learning, food addiction and neuroprotection. Furthermore, ghrelin could promote
overall health and longevity by acting directly in the immune system and promoting an
extended antigen repertoire. The development of mice lacking either ghrelin (ghrelin−/−) or …