[HTML][HTML] Mechanisms of hepatocyte growth factor stimulation of keratinocyte metalloproteinase production
SE Dunsmore, JS Rubin, SO Kovacs, M Chedid… - Journal of Biological …, 1996 - ASBMB
Matrix metalloproteinases participate in normal physiologic processes; however, their
overproduction has been associated with connective tissue destruction in a variety of
pathological states. Migrating basal keratinocytes transiently express collagenase-1 during
normal cutaneous reepithelialization. However, the overexpression of both collagenase-1
and stromelysin-1 has been associated with the pathogenesis of chronic nonhealing ulcers.
Aberrant expression of metalloproteinases in inflammation is mediated, at least in part, by …
overproduction has been associated with connective tissue destruction in a variety of
pathological states. Migrating basal keratinocytes transiently express collagenase-1 during
normal cutaneous reepithelialization. However, the overexpression of both collagenase-1
and stromelysin-1 has been associated with the pathogenesis of chronic nonhealing ulcers.
Aberrant expression of metalloproteinases in inflammation is mediated, at least in part, by …