Signalling shortcuts: cell-surface receptors in the nucleus?
A Wells, U Marti - Nature Reviews Molecular Cell Biology, 2002 - nature.com
A Wells, U Marti
Nature Reviews Molecular Cell Biology, 2002•nature.comDo cell-surface growth-factor receptors and their ligands accumulate in the nucleoplasm
under physiological conditions? And, if so, how do they get there and what function do they
serve in this location? Recent advances have provided tantalizing hints to the answers to
these questions, and hold the key to identifying a new mode of signal transduction.
under physiological conditions? And, if so, how do they get there and what function do they
serve in this location? Recent advances have provided tantalizing hints to the answers to
these questions, and hold the key to identifying a new mode of signal transduction.
Abstract
Do cell-surface growth-factor receptors and their ligands accumulate in the nucleoplasm under physiological conditions? And, if so, how do they get there and what function do they serve in this location? Recent advances have provided tantalizing hints to the answers to these questions, and hold the key to identifying a new mode of signal transduction.
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