Contribution of chloride to the inhibition of plasma renin by sodium chloride in the rat
TA Kotchen, JH Galla, RG Luke - Kidney international, 1978 - Elsevier
TA Kotchen, JH Galla, RG Luke
Kidney international, 1978•ElsevierMethods The basic design of all experiments was similar. In each experiment, 24 male
Sprague Dawley rats were maintained in individual metabolic cages on a low sodium
chloride diet (0 to 1.0 Eq of sodium, 2.0 pEq of chloride per g of diet) for two weeks. Mean
starting weights of all groups of rats ranged from 285 to 315 g. Potassium content of the diet
(determined by nitric acid extraction) varied from 254 EqIg to 387 itEqIg. Animals were given
deionized water to drink during the first week. At the end of this week, the animals were …
Sprague Dawley rats were maintained in individual metabolic cages on a low sodium
chloride diet (0 to 1.0 Eq of sodium, 2.0 pEq of chloride per g of diet) for two weeks. Mean
starting weights of all groups of rats ranged from 285 to 315 g. Potassium content of the diet
(determined by nitric acid extraction) varied from 254 EqIg to 387 itEqIg. Animals were given
deionized water to drink during the first week. At the end of this week, the animals were …
Methods The basic design of all experiments was similar. In each experiment, 24 male Sprague Dawley rats were maintained in individual metabolic cages on a low sodium chloride diet (0 to 1.0 Eq of sodium, 2.0 pEq of chloride per g of diet) for two weeks. Mean starting weights of all groups of rats ranged from 285 to 315 g. Potassium content of the diet (determined by nitric acid extraction) varied from 254 EqIg to 387 itEqIg. Animals were given deionized water to drink during the first week. At the end of this week, the animals were divided into three groups. Within
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