An eleven year old child with a bleeding tendency since infancy is described. The
hemorrhagic disorder was characterized by thrombocytopenia and morphologic
abnormalities of platelets and megakaryocytes, consisting of lack or paucity of granules and
a peculiar gray color. Thrombocytopenia was corrected temporarily by corticosteroid therapy
and permanently by splenectomy. However, morphologic abnormalities, poor clot retraction
and prolonged bleeding time persisted. The platelets aggregated normally with adenosine …