The effects of therapeutic irradiation on lymphocytes and immunity
SE Order - Cancer, 1977 - Wiley Online Library
SE Order
Cancer, 1977•Wiley Online LibraryThe lymphocytotoxic effect of therapeutic irradiation may lead to immune depression. The
significance of such effects is yet to be determined in many malignancies, especially in light
of the persistant immune depression in many “cured” patients. The present review examines
the effects of age, type of cancer, and stage of disease as well as the results of immune
parameters following radiation therapy. Factors to be considered in both the analysis of
present day data and in future studies are also reviewed.
significance of such effects is yet to be determined in many malignancies, especially in light
of the persistant immune depression in many “cured” patients. The present review examines
the effects of age, type of cancer, and stage of disease as well as the results of immune
parameters following radiation therapy. Factors to be considered in both the analysis of
present day data and in future studies are also reviewed.
Abstract
The lymphocytotoxic effect of therapeutic irradiation may lead to immune depression. The significance of such effects is yet to be determined in many malignancies, especially in light of the persistant immune depression in many “cured” patients. The present review examines the effects of age, type of cancer, and stage of disease as well as the results of immune parameters following radiation therapy. Factors to be considered in both the analysis of present day data and in future studies are also reviewed.
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