Micropuncture measurement of interstitial fluid pressure in rat subcutis and skeletal muscle: comparison to wick-in-needle technique

H Wiig, RK Reed, K Aukland - Microvascular research, 1981 - Elsevier
Interstitial fluid pressure (IFP) in subcutis and skeletal muscle of rats has been measured by
sharpened glass capillaries (diameter, 1–3 μm) connected to a servocontrolled
counterpressure system (Wiederhielm). Measurements in subcutis were made by a puncture
through intact skin, while a minute skin incision was made for measurements in skeletal
muscle. Average IFP was− 1.09 mm Hg (SD 0.58, n= 120) in subcutis and− 0.12 mm Hg (SD
0.65, n= 129) in skeletal muscle. Simultaneous measurements with micropipets and with …