Giardia is a protozoan parasite of the small intestine, and a leading cause of diarrhoeal
disease worldwide in a variety of animals, including humans. The host–parasite interaction
and pathophysiological processes of giardiasis remain incompletely understood. Current
research suggests that Giardia-induced diarrhoeal disease is mediated by small intestinal
malabsorption and maldigestion, chloride hypersecretion and increased rates of small
intestinal transit. Small intestinal malabsorption and maldigestion results from the CD8+ …