Expression of endothelin 2 and localized clear cell renal cell carcinoma

BM Bot, JE Eckel-Passow, SN LeGrand, T Hilton… - Human pathology, 2012 - Elsevier
Despite the rising incidence of clear cell renal cell carcinoma, the molecular events that
support its development and progression remain unclear. Herein, we evaluate the
association of endothelin 2 expression with both clear cell renal cell carcinoma development
and progression-free survival. We conducted real-time polymerase chain reaction to
determine endothelin 2 expression levels on 238 patients who underwent nephrectomy for
localized clear cell renal cell carcinoma, 161 of whom also had adjacent normal kidney …