Giardia lamblia infections in adult mice

LG Byrd, JT Conrad, TE Nash - Infection and immunity, 1994 - Am Soc Microbiol
LG Byrd, JT Conrad, TE Nash
Infection and immunity, 1994Am Soc Microbiol
An adult mouse-Giardia lamblia model was developed and used to study host-parasite
interactions, including antigenic variation. The H7/1 clone of isolate GS infected mice
consistently and produced infections in 14 mouse strains tested. Infection patterns were
mouse strain and Giardia isolate dependent. Antigenic variation occurred in
immunocompetent mice but not in mice with severe combined immunodeficiency.
An adult mouse-Giardia lamblia model was developed and used to study host-parasite interactions, including antigenic variation. The H7/1 clone of isolate GS infected mice consistently and produced infections in 14 mouse strains tested. Infection patterns were mouse strain and Giardia isolate dependent. Antigenic variation occurred in immunocompetent mice but not in mice with severe combined immunodeficiency.
American Society for Microbiology