Ultrastructural and histochemical correlations of experimental muscle regeneration

M Reznik, WK Engel - Journal of the Neurological Sciences, 1970 - Elsevier
A correlative ultrastructural and light microscopic histochemical investigation was performed
in cold-injured gastrocnemius muscle in normal adult mice. Three zones were in evidence
after the injury: undamaged muscle, a necrotic area, and an intermediate region. In the
necrotic area, degenerating myofibres contain mainly fragments of myofibrils; they are
stained by the myofibrillar ATP-ase and the menadione-mediated α-glycerophosphate
dehydrogenase reactions. Necrotic fibres are not stained by the reactions for 4 oxidative …