[HTML][HTML] Toward a confocal subcellular atlas of the human proteome
Information on protein localization on the subcellular level is important to map and
characterize the proteome and to better understand cellular functions of proteins. Here we
report on a pilot study of 466 proteins in three human cell lines aimed to allow large scale
confocal microscopy analysis using protein-specific antibodies. Approximately 3000 high
resolution images were generated, and more than 80% of the analyzed proteins could be
classified in one or multiple subcellular compartment (s). The localizations of the proteins …
characterize the proteome and to better understand cellular functions of proteins. Here we
report on a pilot study of 466 proteins in three human cell lines aimed to allow large scale
confocal microscopy analysis using protein-specific antibodies. Approximately 3000 high
resolution images were generated, and more than 80% of the analyzed proteins could be
classified in one or multiple subcellular compartment (s). The localizations of the proteins …