[HTML][HTML] Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5
T Tanoue, T Moriguchi, E Nishida - Journal of Biological Chemistry, 1999 - ASBMB
A group of dual specificity protein phosphatases negatively regulates members of the
mitogen-activated protein kinase (MAPK) superfamily, which consists of three major
subfamilies, MAPK/extracellular signal-regulated kinase (ERK), stress-activated protein
kinase (SAPK)/c-Jun N-terminal kinase (JNK), and p38. Nine members of this group of dual
specificity phosphatases have previously been cloned. They show distinct substrate
specificities for MAPKs, different tissue distribution and subcellular localization, and different …
mitogen-activated protein kinase (MAPK) superfamily, which consists of three major
subfamilies, MAPK/extracellular signal-regulated kinase (ERK), stress-activated protein
kinase (SAPK)/c-Jun N-terminal kinase (JNK), and p38. Nine members of this group of dual
specificity phosphatases have previously been cloned. They show distinct substrate
specificities for MAPKs, different tissue distribution and subcellular localization, and different …