Why do we age?

TBL Kirkwood, SN Austad - Nature, 2000 - nature.com
Nature, 2000nature.com
The evolutionary theory of ageing explains why ageing occurs, giving valuable insight into
the mechanisms underlying the complex cellular and molecular changes that contribute to
senescence. Such understanding also helps to clarify how the genome shapes the ageing
process, thereby aiding the study of the genetic factors that influence longevity and age-
associated diseases.
Abstract
The evolutionary theory of ageing explains why ageing occurs, giving valuable insight into the mechanisms underlying the complex cellular and molecular changes that contribute to senescence. Such understanding also helps to clarify how the genome shapes the ageing process, thereby aiding the study of the genetic factors that influence longevity and age-associated diseases.
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