Rapid evaluation of ethanol content and metabolism in human plasma using quantitative proton magnetic resonance spectroscopy

A Davin, J Vion-Dury, P Viout… - Alcohol and …, 1994 - academic.oup.com
A Davin, J Vion-Dury, P Viout, PJ Cozzone
Alcohol and alcoholism, 1994academic.oup.com
Proton magnetic resonance spectroscopy (MRS) was used to assay ethanol in plasma.
Ethanol concentrations determined by MRS and conventional enzymatic methods are in
excellent agreement. In addition to ethanol, acetone, acetate and β-hydroxybutyrate can be
quantified simultaneously in the same sample. Proton MRS of plasma offers a rapid
evaluation of human ethanol metabolism and may be useful in screening for chronic
alcoholism.
Abstract
Proton magnetic resonance spectroscopy (MRS) was used to assay ethanol in plasma. Ethanol concentrations determined by MRS and conventional enzymatic methods are in excellent agreement. In addition to ethanol, acetone, acetate and β-hydroxybutyrate can be quantified simultaneously in the same sample. Proton MRS of plasma offers a rapid evaluation of human ethanol metabolism and may be useful in screening for chronic alcoholism.
Oxford University Press