Context Impaired mitochondrial function may influence processes highly dependent on
energy, such as neurodevelopment, and contribute to autism. No studies have evaluated
mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined
population of children with autism. Objective To evaluate mitochondrial defects in children
with autism. Design, Setting, and Patients Observational study using data collected from
patients aged 2 to 5 years who were a subset of children participating in the Childhood …