Monocyte chemoattractant protein 1, active carboxypeptidase B and CAPAP at hospital admission are predictive markers for severe acute pancreatitis
S Regnér, S Appelros, C Hjalmarsson, J Manjer… - Pancreatology, 2008 - Elsevier
Background: CAPAP, the activation peptide of procarboxypeptidase B, is a predictor of
severe acute pancreatitis (AP). Active carboxypeptidase (aCAP) may be a better predictor,
as its turnover is slower. Monocyte chemotactic protein-1 (MCP-1) is an early inflammatory
marker and increases before complications in severe AP. We conducted a cohort study to
evaluate these markers as predictors for severe AP. Method: 140 patients with AP were
included, retrospectively grouped as severe or mild by the Atlanta classification. CAPAP …
severe acute pancreatitis (AP). Active carboxypeptidase (aCAP) may be a better predictor,
as its turnover is slower. Monocyte chemotactic protein-1 (MCP-1) is an early inflammatory
marker and increases before complications in severe AP. We conducted a cohort study to
evaluate these markers as predictors for severe AP. Method: 140 patients with AP were
included, retrospectively grouped as severe or mild by the Atlanta classification. CAPAP …