Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection: related to an unfavourable prognosis
B Østerud, T Flaegstad - Thrombosis and haemostasis, 1983 - thieme-connect.com
B Østerud, T Flaegstad
Thrombosis and haemostasis, 1983•thieme-connect.comIn 16 patients, 13 with meningococcal infection and 3 suspected to have this infection, 8
patients were found to possess significant higher level of tissue thromboplastin activity of
their monocytes isolated from the blood at the admission to the hospital than normal. Five of
those 8 patients had an extremely high concentration,> 60-300 fold increase, and all these
patients died. The exposed tissue thromboplastin activity on the surface of the endotoxin
stimulated monocytes is probably the direct inducer of disseminated intravascular …
patients were found to possess significant higher level of tissue thromboplastin activity of
their monocytes isolated from the blood at the admission to the hospital than normal. Five of
those 8 patients had an extremely high concentration,> 60-300 fold increase, and all these
patients died. The exposed tissue thromboplastin activity on the surface of the endotoxin
stimulated monocytes is probably the direct inducer of disseminated intravascular …
In 16 patients, 13 with meningococcal infection and 3 suspected to have this infection, 8 patients were found to possess significant higher level of tissue thromboplastin activity of their monocytes isolated from the blood at the admission to the hospital than normal. Five of those 8 patients had an extremely high concentration, > 60-300 fold increase, and all these patients died. The exposed tissue thromboplastin activity on the surface of the endotoxin stimulated monocytes is probably the direct inducer of disseminated intravascular coagulation (DIC) in meningococcal infection.
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