The thymus constitutes the primary lymphoid organ for the generation of T cells. Its function
is particularly susceptible to various negative influences ranging from age-related involution
to atrophy as a consequence of malnutrition, infection or harmful iatrogenic influences such
as chemotherapy and radiation. The loss of regular thymus function significantly increases
the risk for infections and cancer because of a restricted capacity for immune surveillance. In
recent years, thymus-stimulatory, thymus-regenerative, and thymus-protective strategies …