On why decreasing protein synthesis can increase lifespan
AR Hipkiss - Mechanisms of ageing and development, 2007 - Elsevier
An explanation is offered for the increased lifespan of Caenorhabditis elegans when mRNA
translation is inhibited due to loss of the initiation factor IFE-2 [Hansen, M., Taubert, T.,
Crawford, D., Libina, N., Lee, S.-J., Kenyon, C., 2007. Lifespan extension by conditions that
inhibit translation in Caenorhabditis elegans. Ageing Cell 6, 95–110; Pan, KZ, Palter, JE,
Rogers, AN, Olsen, A., Chen, D., Lithgow, GJ, Kapahi, P., 2007. Inhibition of mRNA
translation extends lifespan in Caenorhabditis elegans. Ageing Cell 6, 111–119; Syntichaki …
translation is inhibited due to loss of the initiation factor IFE-2 [Hansen, M., Taubert, T.,
Crawford, D., Libina, N., Lee, S.-J., Kenyon, C., 2007. Lifespan extension by conditions that
inhibit translation in Caenorhabditis elegans. Ageing Cell 6, 95–110; Pan, KZ, Palter, JE,
Rogers, AN, Olsen, A., Chen, D., Lithgow, GJ, Kapahi, P., 2007. Inhibition of mRNA
translation extends lifespan in Caenorhabditis elegans. Ageing Cell 6, 111–119; Syntichaki …