EWS-ATF1 fusion transcripts in gastrointestinal tumors previously diagnosed as malignant melanoma
M Covinsky, S Gong, V Rajaram, A Perry, J Pfeifer - Human pathology, 2005 - Elsevier
BACKGROUND: Clear cell sarcoma (CCS) is classically a deep soft tissue tumor associated
with tendons or aponeuroses, although cases of primary CCS of the gastrointestinal (GI)
tract have recently been reported. Because it is difficult to distinguish CCS from metastatic
melanoma based on morphology, immunohistochemical profile, and ultrastructural features,
it is possible that some GI tumors diagnosed as metastatic melanoma actually represent
primary GI CCS. Because the EWS-ATF1 fusion transcript and the associated t (12; 22)(q13; …
with tendons or aponeuroses, although cases of primary CCS of the gastrointestinal (GI)
tract have recently been reported. Because it is difficult to distinguish CCS from metastatic
melanoma based on morphology, immunohistochemical profile, and ultrastructural features,
it is possible that some GI tumors diagnosed as metastatic melanoma actually represent
primary GI CCS. Because the EWS-ATF1 fusion transcript and the associated t (12; 22)(q13; …