[HTML][HTML] Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme

A Lai, A Tran, PL Nghiemphu, WB Pope… - Journal of clinical …, 2011 - ncbi.nlm.nih.gov
A Lai, A Tran, PL Nghiemphu, WB Pope, OE Solis, M Selch, E Filka, WH Yong, PS Mischel
Journal of clinical oncology, 2011ncbi.nlm.nih.gov
Purpose This open-label, prospective, multicenter single-arm phase II study combined
bevacizumab (BV) with radiation therapy (RT) and temozolomide (TMZ) for the treatment of
newly diagnosed glioblastoma (GBM). The objectives were to determine the efficacy of this
treatment combination and the associated toxicity.
Abstract
Purpose
This open-label, prospective, multicenter single-arm phase II study combined bevacizumab (BV) with radiation therapy (RT) and temozolomide (TMZ) for the treatment of newly diagnosed glioblastoma (GBM). The objectives were to determine the efficacy of this treatment combination and the associated toxicity.
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