[HTML][HTML] Comparative Immunoproteomics of Identification and Characterization of Virulence Factors from Helicobacter pylori Related to Gastric Cancer* S

YF Lin, MS Wu, CC Chang, SW Lin, JT Lin… - Molecular & Cellular …, 2006 - ASBMB
Helicobacter pylori is an important risk factor of gastric cancer (GC). Although many H. pylori
virulence factors have been reported, the pathogenic mechanism by which H. pylori infection
causes GC remains unclear. The aims of this study were to identify GC-related antigens from
H. pylori and characterize their roles in the development of GC. As GC and duodenal ulcer
(DU) are considered clinically divergent, we compared two-dimensional immunoblots of an
acid-glycine extract of H. pylori probed with serum samples from 15 patients with GC and 15 …