Krüppel-like factors in lymphocyte biology
The Journal of Immunology, 2012•journals.aai.org
The Krüppel-like factor family of transcription factors plays an important role in differentiation,
function, and homeostasis of many cell types. While their role in lymphocytes is still being
determined, it is clear that these factors influence processes as varied as lymphocyte
quiescence, trafficking, differentiation, and function. This review will present an overview of
how these factors operate and coordinate with each other in lymphocyte regulation.
function, and homeostasis of many cell types. While their role in lymphocytes is still being
determined, it is clear that these factors influence processes as varied as lymphocyte
quiescence, trafficking, differentiation, and function. This review will present an overview of
how these factors operate and coordinate with each other in lymphocyte regulation.
Abstract
The Krüppel-like factor family of transcription factors plays an important role in differentiation, function, and homeostasis of many cell types. While their role in lymphocytes is still being determined, it is clear that these factors influence processes as varied as lymphocyte quiescence, trafficking, differentiation, and function. This review will present an overview of how these factors operate and coordinate with each other in lymphocyte regulation.
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