Glycogen synthase kinase (GSK)-3β is a protein kinase in the wingless/wnt pathway and as
such is involved in the regulation of growth and development of the neural tissue in
Drosophila and in vertebrates. This enzyme is also abundantly expressed in the mammal
adult brain, where it might play a role in the regulation of several substrates. The expression
and the neuroanatomical distribution of GSK-3β immunoreactivity in the rat brain from
embryonic up to adult stages has been studied. GSK-3β was expressed in the developing …