Primate neostriatal neurons containing tyrosine hydroxylase: immunohistochemical evidence

M Dubach, R Schmidt, D Kunkel, DM Bowden… - Neuroscience …, 1987 - Elsevier
M Dubach, R Schmidt, D Kunkel, DM Bowden, R Martin, DC German
Neuroscience letters, 1987Elsevier
We have detected, in monkey caudate nucleus and putamen, neuronal cell bodies
containing tyrosine hydroxylase-like immunoreactivity, as revealed by peroxidase-
antiperoxidase immunohistochemistry. Many of these cells are distributed in an outer rim of
1–2 mm throughout the anterior-posterior extent of the neostriatum near its borders with the
corona radiata; others are embedded in the adjacent white matter, especially near the
ventral putamen and nucleus accumbens. Light and electron microscopy indicate that they …
Abstract
We have detected, in monkey caudate nucleus and putamen, neuronal cell bodies containing tyrosine hydroxylase-like immunoreactivity, as revealed by peroxidase-antiperoxidase immunohistochemistry. Many of these cells are distributed in an outer rim of 1–2 mm throughout the anterior-posterior extent of the neostriatum near its borders with the corona radiata; others are embedded in the adjacent white matter, especially near the ventral putamen and nucleus accumbens. Light and electron microscopy indicate that they are small (8–12 μm), bipolar cells with large nuclei. Such neostriatal neurons, containing tyrosine hydroxylase-like immunoreactivity, number in the tens of thousands.
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