Innate and acquired immunity in atherogenesis

CJ Binder, MK Chang, PX Shaw, YI Miller… - Nature medicine, 2002 - nature.com
CJ Binder, MK Chang, PX Shaw, YI Miller, K Hartvigsen, A Dewan, JL Witztum
Nature medicine, 2002nature.com
Traditional risk factors like hypercholesterolemia are important for atherogenesis, but it is
now apparent that the immune system also plays an important role. Uncovering the
mechanisms by which specific components of the immune system impact atherogenesis will
not only provide new insights into the pathogenesis of lesion formation, but could also lead
to novel therapeutic approaches that involve immune modulation.
Traditional risk factors like hypercholesterolemia are important for atherogenesis, but it is now apparent that the immune system also plays an important role. Uncovering the mechanisms by which specific components of the immune system impact atherogenesis will not only provide new insights into the pathogenesis of lesion formation, but could also lead to novel therapeutic approaches that involve immune modulation.
nature.com