CD4+ CD25highCD127low regulatory T cells in patients with stable angina and their dynamics after intracoronary sirolimus-eluting stent implantation
AV Potekhina, SI Provatorov, VO Sokolov… - Human Immunology, 2011 - Elsevier
Rapamycin contributes to the expansion of regulatory T cells (Tregs) in vitro. We
investigated CD4+ CD25 high CD127 low Treg level dynamics as well as the major
parameters of cell immunity and sCD25 and highly sensitive C-reactive protein (hsCRP)
concentrations in the blood of patients after coronary stenting (CS) with sirolimus
(rapamycin)-eluting stents (SES; n= 43). The relation between initial Treg values and the
severity of coronary atherosclerosis was observed. Treg and sCD25 levels were increased 1 …
investigated CD4+ CD25 high CD127 low Treg level dynamics as well as the major
parameters of cell immunity and sCD25 and highly sensitive C-reactive protein (hsCRP)
concentrations in the blood of patients after coronary stenting (CS) with sirolimus
(rapamycin)-eluting stents (SES; n= 43). The relation between initial Treg values and the
severity of coronary atherosclerosis was observed. Treg and sCD25 levels were increased 1 …