The pathogenesis of immune thrombocytopaenic purpura

N Cooper, J Bussel - British journal of haematology, 2006 - Wiley Online Library
N Cooper, J Bussel
British journal of haematology, 2006Wiley Online Library
Immune thrombocytopaenic purpura (ITP) is an autoimmune bleeding disease that is rarely
fatal. However, in many adults treatment is unsatisfactory, with as much morbidity from the
immunosuppressive effects of treatment as from bleeding. Identifying the underlying disease
process should help us to identify more targeted therapies and improve not only the
treatment but also the quality of life of patients with this disorder.
Summary
Immune thrombocytopaenic purpura (ITP) is an autoimmune bleeding disease that is rarely fatal. However, in many adults treatment is unsatisfactory, with as much morbidity from the immunosuppressive effects of treatment as from bleeding. Identifying the underlying disease process should help us to identify more targeted therapies and improve not only the treatment but also the quality of life of patients with this disorder.
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