[HTML][HTML] Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin A in response to epidermal growth factor
M Otsuki, T Itoh, T Takenawa - Journal of Biological Chemistry, 2003 - ASBMB
Neural Wiskott-Aldrich syndrome protein (N-WASP) has been implicated in endocytosis;
however, little is known about how it interacts functionally with the endocytic machinery.
Sucrose gradient fractionation experiments and immunofluorescence studies with anti-N-
WASP antibody revealed that N-WASP is recruited together with clathrin and dynamin,
which play essential roles in clathrin-mediated endocytosis, to lipid rafts in an epidermal
growth factor (EGF)-dependent manner. Endophilin A (EA) binds to dynamin and plays an …
however, little is known about how it interacts functionally with the endocytic machinery.
Sucrose gradient fractionation experiments and immunofluorescence studies with anti-N-
WASP antibody revealed that N-WASP is recruited together with clathrin and dynamin,
which play essential roles in clathrin-mediated endocytosis, to lipid rafts in an epidermal
growth factor (EGF)-dependent manner. Endophilin A (EA) binds to dynamin and plays an …