[HTML][HTML] Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ
Y Jiang, H Gram, M Zhao, L New, J Gu, L Feng… - Journal of Biological …, 1997 - ASBMB
We have cloned and characterized a new member of the p38 group of mitogen-activated
protein kinases here termed p38δ. Sequence comparisons revealed that p38δ is
approximately 60% identical to the other three p38 isoforms but only 40–45% to the other
mitogen-activated protein kinase family members. It contains the TGY dual phosphorylation
site present in all p38 group members and is activated by a group of extracellular stimuli
including cytokines and environmental stresses that also activate the other three known p38 …
protein kinases here termed p38δ. Sequence comparisons revealed that p38δ is
approximately 60% identical to the other three p38 isoforms but only 40–45% to the other
mitogen-activated protein kinase family members. It contains the TGY dual phosphorylation
site present in all p38 group members and is activated by a group of extracellular stimuli
including cytokines and environmental stresses that also activate the other three known p38 …